Asthma Healing

Anaphylactic rhinitis (claim to become in conformity with the sex rhinitis on medical science) and it influence allergy disease of human life quality seriously that asthma all belong to. The ill rate of the two presents the trend increased year by year in the world, and become far higher than asthma in conformity with the ill rate of the sex rhinitis. Thought to become to be two kinds of independent diseases in conformity with sex rhinitis and asthma in the past. Nasal cavity lie in upper respiratory tract, become, belong to ENT dept. disease in conformity with the sex rhinitis; The lung lies in the lower respiratory tracts, so asthma is breathed a physician and made a diagnosis and given treatment. Basically carry on from diagnosing to treating independently too. In recent years, more and more results of study verify: Become with the same kind of constant inflammation diseases while saying at a stretch in conformity with sex rhinitis and asthma. 1997, Grossman of U.S.A. proposes " with saying at a stretch" more clearly even more, " the view of (One Airway, One Disease), in order to emphasize the importance of the globality of upper and lower breathing problems in the same disease.

The close relation that becomes in conformity with sex rhinitis and asthma mainly reflects in three following respects:

一. Epidemiology

There are epidemiology materials that have indicated, become in conformity with the incidence (20%-38%) of asthma of the patients of the sex rhinitis already, obviously higher than the ordinary crowd (2%-5%). And become in the asthma patient in conformity with the incidence of the sex rhinitis 78%, is far higher than the general crowd (5%-20%). Turn into and find alikely that more common among the teenagers lower than 18 years old in conformity with the sex rhinitis and companion of asthma. The overwhelming majority (43%-64%) is shown as and turned into the sex rhinitis first among this part of crowds, asthma happens subsequently; Relatively a few (21%-25%) is shown as the second disease coincides. Therefore, there are extremely close connections in conformity with sex rhinitis and asthma to become.

二. Pathogenesis

It is very close to turn into on the mechanism of having illness coming on of immunology, can stimulate similar tissue pathology to react in upper and lower respiratory tractses to cause quickly separately originally, nasal cavity and bronchus mucous membrane have a large number of complementary T cells which express Th2 cell factor, are addicted to acid cells and loose cells to soak, ergamine, white three alkene, prostaglandin, blood platelet that produce at the same time activate factor, hasten, take inflammation nature mediums such as factor and bradykinin,etc., initiate the similar inflammation reaction process in the upper respiratory tract and lower respiratory tracts. Carry on nose become, should stimulate after the test originally to patient, lower respiratory tracts have a liking for acid cells soak, increase in the mucous membrane, express cell quantity to seize molecule increase, indicate to become, react, might produce similar response in other position in conformity with sex inflammation some mucous membrane at the same time.

三. Treat the principle

Become rhinitis which cause adult's asthma to endanger factor one of while being high in conformity with sex, define two main clinical meaning of connection in having illness coming on in the mechanism lie in, turn into and can lighten symptom of asthma, lower the morbidity of asthma in conformity with the sex rhinitis through treating. Moreover in treat in principle, two have communicating place such as cortex with resist white three alkene medicine become until sex rhinitis as asthma effective treating steroids also. Avoiding contacting cause the quick original and immune treatment to be suitable for becoming in conformity with the sex rhinitis and patient that became in conformity with asthma of sex too.

Seeing that turn it into the sex rhinitis and close relevance of asthma, organized, convened the expert in relevant specialities such as department of throat of nose of more than 30 ears of whole world, allergy subject, division of respiratory disease,etc. in 2001 for this WHO, summarizing turns into and studies the current situation in conformity with the sex rhinitis at present, have written and " turn it into the sex rhinitis and impact on asthma (allergic rhinitis and its impact on asthma, ARIA) " the article, turns into assessing and treating the standard of consulting clinically in conformity with the sex rhinitis as what World Health Organization recommended. In order to cause asthma and doctor of division of respiratory disease correctly of doctor of ear, nose and throat to the attention turned into the sex rhinitis.

 Therefore, though will become in conformity with the sex rhinitis and become regarded as the behavior in different position of a kind of disease and still short of the abundant theoretical foundation briefly in conformity with asthma of sex, but already relatedly approving extensively in having illness coming on in the mechanism of two, the research results of two fields often use the experience of each other for reference too. Define the close relation of the two is of great significance for guiding the clinical treatment: Should be considered to the treatment that became in conformity with the sex rhinitis while treating asthma, the treatment should turn into too like treating asthma, carry on positive, effective intervention and treat, prevent turning into and bringing out or aggravating asthma in conformity with the sex rhinitis.